Genetics: ADPKD

Course Description

This case study illustrates a common clinical scenario (i.e., renal cystic disease in a proband with an inconclusive family history) and many issues related to diagnosis and management of polycystic kidney disease. Original Release: 6/17/2009 Most Recent Update: 1/1/1900 Termination Date: 6/17/2012 NUMBER OF CREDIT HOURS: The Harvard Medical School designates this educational activity for a maximum of 1 AMA PRA Category 1 credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity. COST: $20.00 click here for pricing outside the United States of America OVERALL LEARNING OBJECTIVES: After completing this course, the participant will be able to: Describe the clinical findings associated with autosomal dominant polycystic kidney disease (ADPKD), Understand the genetic basis of ADPKD and related disorders, and Appreciate the issues related to genetic testing in ADPKD. back to the top

Faculty

RAJU KUCHERLAPATI, PHD Course Co-Director Raju Kucherlapati, Ph.D. is the Scientific Director of the Harvard Medical School-Partners HealthCare Center for Genetics and Genomics (HPCGG) and the Paul C. Cabot Professor of Genetics and Professor of Medicine at Harvard Medical School (HMS). He is the first Scientific Director of HPCGG. Dr. Kucherlapati was a member of the consortium to map and sequence the human and mouse genomes. His research interests are in the areas of discovery and characterization of human disease genes using a combination of human and mouse genetic and genomic approaches. He was a member of the National Advisory Council for Human Genome Research at the National Human Genomics Research Institute, co-chair of the steering committee for the National Cancer Institute’s Mouse Models for Human Cancer Consortium and served on the editorial board of the New England Journal of Medicine and was editor in chief of the journal Genomics. He is a fellow of the American Association for the Advancement of Science (AAAS). DISCLOSURE: MARTIN POLLAK, MD Course Co-Director Martin Pollak is an Associate Professor of Medicine at Harvard Medical School. He is an Attending Physician at the Brigham and Women's Hospital in Boston and a board-certified nephrologist. Dr. Pollak received his M.D. degree from New York University, completed a residency in Internal Medicine at Columbia-Presbyterian Medical Center in New York, a clinical nephrology fellowship at the Brigham and Women's Hospital, followed by a post-doctoral fellowship in the Department of Genetics at Harvard Medical School. Dr. Pollak conducts research into the molecular genetic basis of kidney disease. His research laboratory is located in the Harvard Institutes of Medicine building on that Harvard Medical School campus. His laboratory uses a variety of experimental tools to understand the genetic causes of human kidney disease. DISCLOSURE: back to the top

Reviewers

YORK PEI, Reviewer Bio and Photo Coming Soon. DISCLOSURE: THEODORE I. STEINMAN, MD Reviewer Dr. Steinman, a Philadelphia native, received his undergraduate degree from Penn State University (B.S. in Pre-Medicine) and his M.D. degree from Georgetown University School of Medicine in 1964. Internship and junior residency in Internal Medicine were at Cedars-Sinai Medical Center, Los Angeles, CA. Senior medical residency was completed at Beth Israel Hospital, Boston in 1969, following a 2 year tour of duty in the U.S. Navy (1966-1968), serving one year in Vietnam with the Marines. Nephrology Fellowship training was at Tufts New England Medical Center (1969-1971) under the leadership of Drs. William B. Schwartz and Jerome B. Kassirer. From there Dr. Steinman returned to Beth Israel Hospital to start the dialysis and kidney transplantation program, and lead the program for 31 years. Dr. Steinman is a Clinical \ Professor of Medicine, Harvard Medical School and Senior Physician at both Beth Israel Deaconess Medical Center and Brigham and Woman’s Hospital, Boston. Regional and national leadership positions are indicated by his having been President, Renal Physicians Association; Chairman, Scientific Advisory Committee, Polycystic Kidney Foundation; President, National Kidney Foundation Region I; both President and Chairman, National Kidney Foundation of Massachusetts, Rhode Island, New Hampshire, Vermont. He served on the Executive Committee for the Council of American Kidney Societies. He was a member of the Medical Advisory Board, Kidney Disease Outcome Quality Initiative (K/DOQI), which established guidelines of care for patients with kidney disease. He served on the Steering Committee (NIDDK) for the National Kidney Disease Education Program. Currently he sits on the Board of Directors, Polycystic Kidney Disease Foundation and remains an active member of the Medical Advisory Board, NKF of MA, RI, NH, VT. DISCLOSURE: Company: Advance Medical Type of Relationship: Consultant Content Area: 2nd Medical Opinion TERRY WATNICK, Reviewer Bio and Photo Coming Soon. DISCLOSURE: RANDY WERTHEIMER, Reviewer Bio and Photo Coming Soon. DISCLOSURE: back to the top

Accreditation

NUMBER OF CREDITS: 1  Harvard Medical School is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. The Harvard Medical School designates this educational activity for a maximum of 1 AMA PRA Category 1 credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity. Upon completion of the course you will get a certificate via e-mail within 2 weeks. Click the image to view a sample of the certificate back to the top

General Information

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